Transcriptomics and Proteomics – Genomics News and Views

Hacking the viral proteome to block infection progression

Scientists have adapted existing technology to understand the interactions between the proteins on the surface of pathogenic viruses and the proteins on our body’s cells that allow infection to establish successfully. Disclaimer: “This web page was produced as an assignment for an undergraduate course at Davidson College.” Jumbophages on the surface of a host cell…

Diving into Brain Diversity: Analyzing RNA to Study Gene Expression

This web page was produced as an assignment for an undergraduate course at Davidson College. The regions associated with brain disorders vary therefore it can be hypothesized that the turning off and on genes (gene expression) in different parts of the brain is crucial to how brain diseases affect specific regions of the brain. Evidence…

The harmonious dance of genomic and transcriptome in schooling fish

Fish schooling offers a useful model for examining the genetic makeup of affiliative behaviors and analyzing the mechanisms underlying these species’ social behaviors and personality traits. This web page was produced as an assignment for an undergraduate course at Davidson College. Many animals across the animal kingdom develop complex social behaviors that seem to be…

A New Light on Parkinson’s Disease

After careful sequencing and identification of different cell strains, Q. Wang et al. found convincing evidence that Parkinson’s Disease impacts more of the brain than we thought. This web page was produced as an assignment for an undergraduate course at Davidson College. Since its discovery in 1817, Parkinson’s Disease has been a notorious neurological disorder…

Picture of a white lab mouse with red eyes being held by a scientist wearing latex gloves. The mouse is being injected with a syringe containing red liquid, which is implied to be an opioid. Retrieved from The Scientist

Whiskers and Withdrawal: Molecular Insights into Opioid Use Disorder in Male Mouse Models

Summary Mouse models help unravel the mysteries of opioid addiction through analysis of the molecular changes in the brain triggered by heroin use. Comparison of these findings with human data pinpoints shared genetic patterns, shedding light on potential treatments for opioid use disorder. News and Views by: Ella Wuichet (elwuichet@davidson.edu) Primary Article: Caleb J. Browne…

The Eternal Fight: An Interdisciplinary Approach to Cancer Diagnosis

In a world where artificial intelligence is all around us, how can we harness this technology to aid health outcomes? A talented group of scientists attempt to answer this question by creating a novel machine learning algorithm that could potentially mark the beginning of a new era of non-invasive cancer diagnostic tests. This web page…

Deciphering the chromatin landscape and epigenetic shenanigans in healthy and adaptive kidney cells

Disclaimer: This web page was produced as an assignment for an undergraduate course at Davidson College. A comprehensive genome-wide atlas of epigenetic profiles in gene regulatory regions unveils differences between healthy and adaptive kidney cells, shedding light on potential therapeutic targets for kidney repair. Kidney cells exhibit gene expression changes after being exposed to damage…

A’s, T’s, and Kidney Disease

The methylation of human DNA can provide insight into the risk factors and development of renal disease. This web page was produced as an assignment for an undergraduate course at Davidson College. The field of genomics has rapidly expanded in recent years and provided new understanding of how our genes are expressed, especially in relation…

There is a bug in my stomach! How Machine Learning can be used to predict Crohn’s Disease Progression

Development of Machine Learning techniques gives accurate medical predictions of the development of Pediatric Crohn’s Disease Disclaimer: This web page was produced as an assignment for an undergraduate course at Davidson College. Images courtesy of Liz Zhang, MD. Catherine E. Hagen, MD., Luisa Ricaurte Archila, MD. Crohn’s Disease (CD) is an inflammatory bowel disease where…

Evolutionary Adaptations to High Elevations

Photo Courtesy of Pest Control Technology Specialized deer mice have evolved physiological adaptations geared towards better fetal growth outcomes in spite of low-oxygen environments. Disclaimer: This web page was produced as an assignment for an undergraduate course at Davidson College. Oxygen has been deemed the ‘elixir of life’ ever since its atomic discovery in the…

Category: Transcriptomics and Proteomics